It also allows discovery of novel exons, genes and splice junction.
2.
Splice junctions were validated if a minimum of 10 reads with the following characteristics spanned the predicted splice junctions.
3.
Splice junctions were validated if a minimum of 10 reads with the following characteristics spanned the predicted splice junctions.
4.
The domains radiate from a central core that brings the 5'and 3'splice junctions into close proximity.
5.
EJCs are multiprotein complexes that assemble during splicing at a position about 20-24 nucleotides upstream from the splice junction.
6.
A special GenomeThesaurus is also provided for potential splice junctions, which allows for splice junction analysis and identification of new transcriptional units.
7.
A special GenomeThesaurus is also provided for potential splice junctions, which allows for splice junction analysis and identification of new transcriptional units.
8.
The genes in the genomes of these organisms are also split into exons and introns, and exhibit basically the same splice junction sequences.
9.
The project involves the systematic screening of coding genes and flanking splice junctions of all genes in the human genome for acquired mutations in human cancers.
10.
Splicing " silencers " are sites to which splicing repressor proteins bind, reducing the probability that a nearby site will be used as a splice junction.
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